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When applying a retinol-infused elixir, don’t neglect your neck or décolletage, which are areas notorious for showing the signs of aging, yet often overlooked. “If those zones seem too sensitive for your current formula, add a squirt of ceramide-enriched moisturizer before smoothing it on, or pick up a separate retinoid made specifically for the area in question,” says Bowe. “They typically contain a lower dose of vitamin A, zero fragrance, and loads of soothers.”

Oregon Ducks Big 10 Conference Champions Beat Penn State 2024 T-Shirts

“Although retinoids are not phototoxic, meaning they won’t react with sunlight to cause a burn on the skin the way lime juice can, many of them do break down when exposed to UV rays,” explains Bowe. “So applying your retinoid in the morning might render it less effective, and a high-quality retinoid can be quite pricey. That’s why I recommend using your retinol, or your retinal (my personal favorite retinoid, which is 10x more bioavailable than retinol) at night.” For proper sun safety, Bowe recommends being diligent about applying a daily broad-spectrum SPF 30 or higher during the day. Moreover, with retinol use, one should always be conscious of the weather forecast and trips to hot locales. “It should not be used during seasons or vacations when individuals will be spending extended time in direct sunlight,” warns Fusco.

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While certain side effects, such as mild irritation, dryness, and sun sensitivity, are normal as your skin adjusts to the active ingredient, intense flaking, redness, and burning are not and those with especially sensitive skin, or who struggle with conditions like rosacea or eczema, should be wary of retinol or shy away from it altogether. “If you cannot tolerate retinol, don’t worry,” says Marmur. “It’s not the only anti-ager! There are plenty of amazing anti-aging ingredients, such as wild indigo, that work beautifully without any irritation or sun sensitivity.”

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